Neuropsychology of traumatic brain injury: An expert overview

Traumatic brain injury (TBI) is a serious healthcare problem, and this report is a selective review of recent findings on the epidemiology, pathophysiology and neuropsychological impairments following TBI. Patients who survive moderate-to-severe TBI frequently suffer from a wide range of cognitive d...

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Bibliographic Details
Published in:Revue neurologique Vol. 173; no. 7-8; pp. 461 - 472
Main Authors: Azouvi, P., Arnould, A., Dromer, E., Vallat-Azouvi, C.
Format: Journal Article
Language:English
Published: France Elsevier Masson SAS 01.07.2017
Elsevier Masson
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ISSN:0035-3787
Online Access:Get full text
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Summary:Traumatic brain injury (TBI) is a serious healthcare problem, and this report is a selective review of recent findings on the epidemiology, pathophysiology and neuropsychological impairments following TBI. Patients who survive moderate-to-severe TBI frequently suffer from a wide range of cognitive deficits and behavioral changes due to diffuse axonal injury. These deficits include slowed information-processing and impaired long-term memory, attention, working memory, executive function, social cognition and self-awareness. Mental fatigue is frequently also associated and can exacerbate the consequences of neuropsychological deficits. Personality and behavioral changes can include combinations of impulsivity and apathy. Even mild TBI raises specific problems: while most patients recover within a few weeks or months, a minority of patients may suffer from long-lasting symptoms (post-concussion syndrome). The pathophysiology of such persistent problems remains a subject of debate, but seems to be due to both injury-related and non-injury-related factors.
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ISSN:0035-3787
DOI:10.1016/j.neurol.2017.07.006