Glyco-genes change expression in cancer through aberrant methylation

Most eukaryotic proteins are modified by covalent addition of glycan molecules that considerably influence their function. Aberrant glycosylation is profoundly involved in malignant transformation, tumor progression and metastasis. Some glycan structures are tumor-specific and reflect disturbed glyc...

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Vydáno v:	Biochimica et biophysica acta Ročník 1860; číslo 8; s. 1776 - 1785
Hlavní autoři:	Vojta, Aleksandar, Samaržija, Ivana, Bočkor, Luka, Zoldoš, Vlatka
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier B.V 01.08.2016
Témata:	biosynthesis brain Cancer data collection Databases, Genetic DNA Methylation DNA, Neoplasm - genetics DNA, Neoplasm - metabolism Epigenesis, Genetic Epigenetics Female Gene expression Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic genes glycosylation Humans lung neoplasms lymph nodes Male mannosidases medicine melanoma metastasis Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Neoplasms - enzymology Neoplasms - genetics polysaccharides prognosis Promoter Regions, Genetic Protein glycosylation proteins transferases DNA methylation Epigenetics Protein glycosylation Gene expression Cancer
ISSN:	0304-4165, 0006-3002, 1872-8006
On-line přístup:	Získat plný text
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