Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis

Regnase-1 and Roquin are RNA binding proteins that are essential for degradation of inflammatory mRNAs and maintenance of immune homeostasis. Although deficiency of either of the proteins leads to enhanced T cell activation, their functional relationship in T cells has yet to be clarified because of...

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Veröffentlicht in:The Journal of immunology (1950) Jg. 199; H. 12; S. 4066
Hauptverfasser: Cui, Xiaotong, Mino, Takashi, Yoshinaga, Masanori, Nakatsuka, Yoshinari, Hia, Fabian, Yamasoba, Daichi, Tsujimura, Tohru, Tomonaga, Keizo, Suzuki, Yutaka, Uehata, Takuya, Takeuchi, Osamu
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 15.12.2017
ISSN:1550-6606, 1550-6606
Online-Zugang:Weitere Angaben
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