Five-Year Outcomes after Off-Pump or On-Pump Coronary-Artery Bypass Grafting

After 5 years of follow-up in this trial, the rates of the composite outcome of death, stroke, myocardial infarction, renal failure, or repeat revascularization were similar with off-pump and on-pump CABG. There was also no significant difference in cost or in quality of life. Coronary-artery bypass...

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Vydáno v:The New England journal of medicine Ročník 375; číslo 24; s. 2359 - 2368
Hlavní autoři: Lamy, André, Devereaux, P.J, Prabhakaran, Dorairaj, Taggart, David P, Hu, Shengshou, Straka, Zbynek, Piegas, Leopoldo S, Avezum, Alvaro, Akar, Ahmet R, Lanas Zanetti, Fernando, Jain, Anil R, Noiseux, Nicolas, Padmanabhan, Chandrasekar, Bahamondes, Juan-Carlos, Novick, Richard J, Tao, Liang, Olavegogeascoechea, Pablo A, Airan, Balram, Sulling, Toomas-Andres, Whitlock, Richard P, Ou, Yongning, Gao, Peggy, Pettit, Shirley, Yusuf, Salim
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Massachusetts Medical Society 15.12.2016
Témata:
Aged
Bypass
Cerebral infarction
Clinical outcomes
Clinical trials
Coronary artery
Coronary Artery Bypass - economics
Coronary Artery Bypass - methods
Coronary Artery Bypass, Off-Pump
Coronary Artery Disease - mortality
Coronary Artery Disease - surgery
Coronary vessels
Death
Female
Follow-Up Studies
Heart
Heart diseases
Heart surgery
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Myocardial infarction
Myocardial Infarction - etiology
Postoperative Complications - epidemiology
Proportional Hazards Models
Quality of Life
Renal failure
Renal Insufficiency - etiology
Reoperation - statistics & numerical data
Stroke
Stroke - etiology
Surgical techniques
ISSN:0028-4793, 1533-4406, 1533-4406
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Shrnutí:After 5 years of follow-up in this trial, the rates of the composite outcome of death, stroke, myocardial infarction, renal failure, or repeat revascularization were similar with off-pump and on-pump CABG. There was also no significant difference in cost or in quality of life. Coronary-artery bypass grafting (CABG) reduces the risk of death in patients with extensive coronary artery disease. 1 CABG is usually performed with the use of a cardiopulmonary bypass (on-pump CABG). With this approach, perioperative mortality is approximately 2%, with an additional 5 to 9% of patients having myocardial infarction, stroke, or renal failure requiring dialysis. The technique of performing CABG on a beating heart (off-pump CABG) was developed to decrease the risk of perioperative complications and to improve long-term outcomes; some complications, both perioperative and long term, may be related to the use of cardiopulmonary bypass and to cross-clamping of the . . .
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa1601564