Autophagy in kidney disease and aging: lessons from rodent models

Autophagy is a highly regulated lysosomal protein degradation pathway that removes protein aggregates and damaged or excess organelles to maintain intracellular homeostasis and cell integrity. Dysregulation of autophagy is involved in the pathogenesis of a variety of metabolic and age-related diseas...

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Veröffentlicht in:	Kidney international Jg. 90; H. 5; S. 950 - 964
Hauptverfasser:	Lenoir, Olivia, Tharaux, Pierre-Louis, Huber, Tobias B
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.11.2016
Schlagworte:	Aging - physiology Animals Autophagy Kidney Diseases - physiopathology endothelium kidney autophagy polycystic kidney disease kidney transplantation podocyte mTOR acute kidney injury aging glomerulus
ISSN:	1523-1755
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