Involvement of RAGE in radiation-induced acquisition of malignant phenotypes in human glioblastoma cells

Glioblastoma (GBM), a highly aggressive malignant tumor of the central nervous system, is mainly treated with radiotherapy. However, since irradiation may lead to the acquisition of migration ability by cancer cells, thereby promoting tumor metastasis and invasion, it is important to understand the...

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Veröffentlicht in:	Biochimica et biophysica acta. General subjects Jg. 1868; H. 9; S. 130650
Hauptverfasser:	Seki, Hiromu, Kitabatake, Kazuki, Tanuma, Sei-ichi, Tsukimoto, Mitsutoshi
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Netherlands Elsevier B.V 01.09.2024
Schlagworte:	actin Benzamides Brain Neoplasms - metabolism Brain Neoplasms - pathology Brain Neoplasms - radiotherapy Cell Line, Tumor Cell migration cell movement Cell Movement - radiation effects central nervous system Gamma Rays Glioblastoma Glioblastoma - metabolism Glioblastoma - pathology Glioblastoma - radiotherapy HMGB1 HMGB1 Protein - metabolism Humans irradiation metastasis nucleoproteins Phenotype phosphorylation Phosphorylation - radiation effects Pyruvates - pharmacology pyruvic acid Radiation radiotherapy RAGE Receptor for Advanced Glycation End Products - metabolism Signal Transduction STAT3 STAT3 Transcription Factor - metabolism RAGE HMGB1 Cell migration Glioblastoma Radiation STAT3
ISSN:	0304-4165, 1872-8006, 1872-8006
Online-Zugang:	Volltext
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