Ceritinib-related interstitial lung disease improving after treatment cessation without recurrence under either crizotinib or brigatinib: a case report
Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed follow...
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| Vydáno v: | Annals of translational medicine Ročník 7; číslo 5; s. 106 |
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| Hlavní autoři: | , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
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China
01.03.2019
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| ISSN: | 2305-5839, 2305-5839 |
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| Abstract | Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi. |
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| AbstractList | Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi. Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi.Anaplastic lymphoma kinase inhibitors (ALKi) like ceritinib are considered standard for front-line treatment of non-small cell lung cancers (NSCLC) harboring a translocation of the anaplastic lymphoma kinase (ALK) gene. We report herein a case of interstitial lung disease (ILD) that developed following a 7-month ceritinib treatment without recurrence under either crizotinib or brigatinib, two others ALKi. |
| Author | Meyer, Guillaume Quoix, Elisabeth Mennecier, Bertrand Bender, Laura |
| Author_xml | – sequence: 1 givenname: Laura surname: Bender fullname: Bender, Laura organization: Department of Medical Oncology, University Hospital, Strasbourg, France – sequence: 2 givenname: Guillaume surname: Meyer fullname: Meyer, Guillaume organization: Department of Pharmacy, University Hospital, Strasbourg, France – sequence: 3 givenname: Elisabeth surname: Quoix fullname: Quoix, Elisabeth organization: Department of Pneumology, University Hospital, Strasbourg, France – sequence: 4 givenname: Bertrand surname: Mennecier fullname: Mennecier, Bertrand organization: Department of Pneumology, University Hospital, Strasbourg, France |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31019956$$D View this record in MEDLINE/PubMed |
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| Keywords | Anaplastic lymphoma kinase rearrangement (ALK rearrangement) diffuse interstitial pneumonitis ceritinib non-small cell lung cancer (NSCLC) |
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| Title | Ceritinib-related interstitial lung disease improving after treatment cessation without recurrence under either crizotinib or brigatinib: a case report |
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