A Semi-Automated Algorithm for Segmentation of the Left Atrial Appendage Landing Zone: Application in Left Atrial Appendage Occlusion Procedures

Abstract Background: Mechanical occlusion of the Left atrial appendage (LAA) using a purpose-built device has emerged as an effective prophylactic treatment in patients with atrial fibrillation at risk of stroke and a contraindication for anticoagulation. A crucial step in procedural planning is the...

Full description

Saved in:
Bibliographic Details
Published in:Journal of biomedical physics and engineering Vol. 10; no. 2; pp. 205 - 214
Main Author: A, Pakizeh Moghadam
Format: Journal Article
Language:English
Published: Iran Shiraz University of Medical Sciences 01.04.2020
Subjects:
ISSN:2251-7200, 2251-7200
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Background: Mechanical occlusion of the Left atrial appendage (LAA) using a purpose-built device has emerged as an effective prophylactic treatment in patients with atrial fibrillation at risk of stroke and a contraindication for anticoagulation. A crucial step in procedural planning is the choice of the device size. This is currently based on the manual analysis of the “Device Landing Zone” from echocardiographic images. Objective: We aimed to develop an algorithm for automated segmentation of the LAA landing zone from 3D echocardiographic images of the LAA. Material and Methods: In this experimental study, 2D axial images were derived from the 3D echo datasets. After image pre-processing, binary images were created using a thresholding method. A binary image matrix was then formed and scanned using 8-adgacency approach resulting in segmentation of the objects with a closed circumference within the image. Erosion/dilation techniques were then applied to remove small objects. A feature-based approach was then used to firstly detect the LAA region and secondly to identify the device landing zone. Results: A total of 22 datasets were used in this study. The algorithm produced up to 9 axial images as the proposed landing zone. The selected axial images were compared to the echocardiographic images. In 18 cases (81.8%), the algorithm successfully segmented the LAA and proposed the landing zone based on the defined features. Conclusion: We have developed a simple and fast algorithm for semi-automated segmentation of the LAA landing zone. Further studies are needed to assess the accuracy of the proposed landing zones by this method.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2251-7200
2251-7200
DOI:10.31661/jbpe.v0i0.1912-1019