Challenges in undertaking nonlinear Mendelian randomization

Mendelian randomization (MR) is a widely used method that exploits the unique properties of germline genetic variation to strengthen causal inference in relationships between exposures and outcomes. Nonlinear MR allows estimation of the shape of these relationships. In a previous paper, the authors...

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Vydané v:	Obesity (Silver Spring, Md.) Ročník 31; číslo 12; s. 2887 - 2890
Hlavní autori:	Wade, Kaitlin H., Hamilton, Fergus W., Carslake, David, Sattar, Naveed, Davey Smith, George, Timpson, Nicholas J.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Blackwell Publishing Ltd 01.12.2023
Predmet:	Bias Biobanks Body Mass Index Cardiovascular disease Causality Diabetes Estimates Genome-Wide Association Study Medical research Mendelian Randomization Analysis Methods Mortality Obesity Vitamin D United Kingdom > UK
ISSN:	1930-7381, 1930-739X, 1930-739X
On-line prístup:	Získať plný text
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