Challenges in undertaking nonlinear Mendelian randomization

Mendelian randomization (MR) is a widely used method that exploits the unique properties of germline genetic variation to strengthen causal inference in relationships between exposures and outcomes. Nonlinear MR allows estimation of the shape of these relationships. In a previous paper, the authors...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Jg. 31; H. 12; S. 2887 - 2890
Hauptverfasser:	Wade, Kaitlin H., Hamilton, Fergus W., Carslake, David, Sattar, Naveed, Davey Smith, George, Timpson, Nicholas J.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Blackwell Publishing Ltd 01.12.2023
Schlagworte:	Bias Biobanks Body Mass Index Cardiovascular disease Causality Diabetes Estimates Genome-Wide Association Study Medical research Mendelian Randomization Analysis Methods Mortality Obesity Vitamin D United Kingdom > UK
ISSN:	1930-7381, 1930-739X, 1930-739X
Online-Zugang:	Volltext
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