Quantitative susceptibility mapping versus phase imaging to identify multiple sclerosis iron rim lesions with demyelination

Background and Purpose To compare quantitative susceptibility mapping (QSM) and high‐pass‐filtered (HPF) phase imaging for (1) identifying chronic active rim lesions with more myelin damage and (2) distinguishing patients with increased clinical disability in multiple sclerosis. Methods Eighty patie...

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Bibliographic Details
Published in:	Journal of neuroimaging Vol. 32; no. 4; pp. 667 - 675
Main Authors:	Huang, Weiyuan, Sweeney, Elizabeth M., Kaunzner, Ulrike W., Wang, Yi, Gauthier, Susan A., Nguyen, Thanh D.
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.07.2022
Subjects:	Brain - pathology chronic active lesions Damage Demyelination high‐pass‐filtered phase imaging Humans Image Interpretation, Computer-Assisted - methods Iron Lesions Magnetic resonance imaging Magnetic Resonance Imaging - methods Mapping Medical imaging Multiple sclerosis Multiple Sclerosis - diagnostic imaging Multiple Sclerosis - pathology Myelin Myelin Sheath - pathology myelin water fraction (MWF) Neuroimaging paramagnetic rim Patients quantitative susceptibility mapping (QSM) Regression models Statistical analysis Water high-pass-filtered phase imaging chronic active lesions quantitative susceptibility mapping (QSM) paramagnetic rim multiple sclerosis myelin water fraction (MWF)
ISSN:	1051-2284, 1552-6569, 1552-6569
Online Access:	Get full text
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