Severe and protracted cholestasis in 44 young men taking bodybuilding supplements: assessment of genetic, clinical and chemical risk factors

Summary Background Bodybuilding supplements can cause a profound cholestatic syndrome. Aim To describe the drug‐Induced liver injury network's experience with liver injury due to bodybuilding supplements. Methods Liver injury pattern, severity and outcomes, potential genetic associations, and e...

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Bibliographic Details
Published in:	Alimentary pharmacology & therapeutics Vol. 49; no. 9; pp. 1195 - 1204
Main Authors:	Stolz, Andrew, Navarro, Victor, Hayashi, Paul H., Fontana, Robert J., Barnhart, Huiman X., Gu, Jiezhun, Chalasani, Naga P., Vega, Maricruz M., Bonkovsky, Herbert L., Seeff, Leonard B., Serrano, Jose, Avula, Bharathi, Khan, Ikhlas A., Cirulli, Elizabeth T., Kleiner, David E., Hoofnagle, Jay H.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01.05.2019
Subjects:	Adult ATP Binding Cassette Transporter, Subfamily B, Member 11 - genetics Bile Bile ducts Biopsy Bodybuilding Chemical and Drug Induced Liver Injury - epidemiology Chemical and Drug Induced Liver Injury - genetics Chemical and Drug Induced Liver Injury - pathology Cholestasis Cholestasis - chemically induced Cholestasis - epidemiology Cholestasis - genetics Cholestasis - therapy Dietary Supplements - adverse effects Dietary Supplements - analysis Fibrosis Gallbladder diseases Genetic diversity Genetic Predisposition to Disease - epidemiology Hepatitis Humans Jaundice Latency Liver Liver transplantation Liver Transplantation - statistics & numerical data Male Middle Aged Muscles - drug effects Muscles - pathology Performance-Enhancing Substances - adverse effects Performance-Enhancing Substances - analysis Performance-Enhancing Substances - chemistry Pruritus Risk Factors Severity of Illness Index Somatotypes - physiology Steroid hormones Young Adult
ISSN:	0269-2813, 1365-2036, 1365-2036
Online Access:	Get full text
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