Opposing Intermolecular Tuning of Ca2+ Affinity for Calmodulin by Neurogranin and CaMKII Peptides

We investigated the impact of bound calmodulin (CaM)-target compound structure on the affinity of calcium (Ca2+) by integrating coarse-grained models and all-atomistic simulations with nonequilibrium physics. We focused on binding between CaM and two specific targets, Ca2+/CaM-dependent protein kina...

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Bibliographic Details

Published in:	Biophysical journal Vol. 112; no. 6; p. 1105
Main Authors:	Zhang, Pengzhi, Tripathi, Swarnendu, Trinh, Hoa, Cheung, Margaret S
Format:	Journal Article
Language:	English
Published:	28.03.2017
ISSN:	1542-0086, 1542-0086
Online Access:	Get more information
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