QT Interval Prolongation with One or More QT-Prolonging Agents Used as Part of a Multidrug Regimen for Rifampicin-Resistant Tuberculosis Treatment: Findings from Two Pediatric Studies

Rifampicin-resistant tuberculosis (RR-TB) involves treatment with many drugs that can prolong the QT interval; this risk may increase when multiple QT-prolonging drugs are used together. We assessed QT interval prolongation in children with RR-TB receiving one or more QT-prolonging drugs. Data were...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy Jg. 67; H. 7; S. e0144822
Hauptverfasser:	Ali, Ali Mohamed, Radtke, Kendra K, Hesseling, Anneke C, Winckler, Jana, Schaaf, H Simon, Draper, Heather R, Solans, Belén P, van der Laan, Louvina, Hughes, Jennifer, Fourie, Barend, Nielsen, James, Garcia-Prats, Anthony J, Savic, Rada M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 18.07.2023
Schlagworte:	Adolescent Antitubercular Agents - adverse effects Child Child, Preschool Clofazimine - therapeutic use Electrocardiography Humans Levofloxacin - therapeutic use Rifampin - therapeutic use South Africa Tuberculosis, Multidrug-Resistant - drug therapy South Africa QT prolongation drug-drug interaction pediatrics tuberculosis
ISSN:	1098-6596, 1098-6596
Online-Zugang:	Weitere Angaben
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