Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: A randomized trial

To determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment. Three prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjec...

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Vydáno v:The Angle orthodontist Ročník 89; číslo 3; s. 365 - 371
Hlavní autoři: Kau, Chung H., Wang, Jue, Palombini, Anna, Abou-Kheir, Nadia, Christou, Terpsithea
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Edward H. Angle Society of Orthodontists 01.05.2019
Témata:
Cariostatic Agents
Dental Caries - prevention & control
Dentifrices - therapeutic use
Fluorides
Humans
Original
Prospective Studies
Tooth Movement Techniques
Tooth Remineralization
Dental caries
Toothpastes
Enamel decalcification
Fluorides
Tooth demineralization
Randomized controlled trial
ISSN:0003-3219, 1945-7103, 1945-7103
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Shrnutí:To determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment. Three prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjects). The selected product was brushed on for 2 minutes twice daily for 4 months. Subjects were reviewed for 4 months on a monthly basis. The Enamel Decalcification Index (EDI) was used to determine the number of white spot lesions per surface at each visit. 100 subjects (35 using Clinpro 5000, 32 using Clinpro Tooth Crème, and 33 using MI Paste Plus) completed the study. The data lend strong support for Clinpro 5000 providing superior protection against enamel decalcification when compared to Clinpro Crème, and mixed support when compared to MI Paste Plus. The use of Clinpro 5000, Clinpro Crème, and MI paste Plus all have a reduction effect on white spot lesions when compared to studies reported previously. Clinpro 5000 has a marginally better effect than the two other test pastes. The results of this study can be used by clinicians when deciding the effectiveness of using fluoride dentifrice products to prevent white spot lesions in their orthodontic practice (ClinicalTrials.gov ID: NCT03440996).
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Assistant Professor, Department of Orthodontics, School of Dentistry, Univeristy of Alabama at Birmingham, Birmingham, Ala, USA.
Former Orthodontic Resident, Department of Orthodontics, School of Dentistry, Univeristy of Alabama at Birmingham, Birmingham, Ala, USA.
Professor and Chairman, Department of Orthodontics, School of Dentistry, Univeristy of Alabama at Birmingham, Birmingham, Ala, USA.
Orthodontic Resident, Department of Orthodontics, School of Dentistry, Univeristy of Alabama at Birmingham, Birmingham, Ala, USA.
ISSN:0003-3219
1945-7103
1945-7103
DOI:10.2319/051818-371.1