Gasdermins and their role in immunity and inflammation

The gasdermins are a family of pore-forming proteins recently implicated in the immune response. One of these proteins, gasdermin D (GSDMD), has been identified as the executioner of pyroptosis, an inflammatory form of lytic cell death that is induced upon formation of caspase-1-activating inflammas...

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Bibliographic Details
Published in:The Journal of experimental medicine Vol. 216; no. 11; p. 2453
Main Authors: Orning, Pontus, Lien, Egil, Fitzgerald, Katherine A
Format: Journal Article
Language:English
Published: United States 04.11.2019
ISSN:1540-9538, 1540-9538
Online Access:Get more information
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