Discogenic Low Back Pain: Anatomy, Pathophysiology and Treatments of Intervertebral Disc Degeneration

Intervertebral disc (IVD) degeneration is a major contributing factor for discogenic low back pain (LBP), causing a significant global disability. The IVD consists of an inner core proteoglycan-rich nucleus pulposus (NP) and outer lamellae collagen-rich annulus fibrosus (AF) and is confined by a car...

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Bibliographic Details

Published in:	International journal of molecular sciences Vol. 24; no. 1; p. 208
Main Authors:	Mohd Isa, Isma Liza, Teoh, Seong Lin, Mohd Nor, Nurul Huda, Mokhtar, Sabarul Afian
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI 22.12.2022
Subjects:	Annulus Fibrosus - metabolism Back Pain - pathology Cartilage - metabolism Humans Intervertebral Disc - metabolism Intervertebral Disc Degeneration - metabolism Low Back Pain - etiology Low Back Pain - therapy Review intervertebral disc degeneration pain mechanisms discogenic low back pain innervation inflammation
ISSN:	1422-0067, 1422-0067
Online Access:	Get full text
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