Ultrasensitive Clostridioides difficile Toxin Testing for Higher Diagnostic Accuracy

Currently available diagnostic tests for infection (CDI) lack specificity or sensitivity, which has led to guideline recommendations for multistep testing algorithms. Ultrasensitive assays for detection of toxins provide measurements of disease-specific markers at very low concentrations. These assa...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Journal of clinical microbiology Ročník 58; číslo 6
Hlavní autoři: Sandlund, Johanna, Davies, Kerrie, Wilcox, Mark H
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States 26.05.2020
Témata:
ultrasensitive
Clostridioides difficile
toxin
diarrhea
Clostridium difficile
ISSN:1098-660X, 1098-660X
On-line přístup:Zjistit podrobnosti o přístupu
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Currently available diagnostic tests for infection (CDI) lack specificity or sensitivity, which has led to guideline recommendations for multistep testing algorithms. Ultrasensitive assays for detection of toxins provide measurements of disease-specific markers at very low concentrations. These assays may show improved accuracy compared to that of current testing methods and offer a potential standalone solution for CDI diagnosis, although large studies of clinical performance and accuracy are lacking.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1098-660X
1098-660X
DOI:10.1128/JCM.01913-19