Drug-induced ototoxicity: Mechanisms, Pharmacogenetics, and protective strategies

Drug ototoxicity limits the quality of life of patients after treatment, having serious consequences, especially for psychosocial development of children. Although the ototoxicity of many drugs resolves after treatment discontinuation, the use of platinum derivatives and aminoglycosides is associate...

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Bibliographic Details

Published in:	Clinical pharmacology and therapeutics Vol. 101; no. 4; p. 491
Main Authors:	Lanvers-Kaminsky, C, Zehnhoff-Dinnesen, Ag Am, Parfitt, R, Ciarimboli, G
Format:	Journal Article
Language:	English
Published:	United States 01.04.2017
Subjects:	Aminoglycosides - adverse effects Animals Antineoplastic Agents - adverse effects Child Drug-Related Side Effects and Adverse Reactions - epidemiology Drug-Related Side Effects and Adverse Reactions - genetics Drug-Related Side Effects and Adverse Reactions - prevention & control Ear - physiopathology Hearing Loss - chemically induced Hearing Loss - epidemiology Hearing Loss - genetics Hearing Loss - physiopathology Hearing Loss - prevention & control Humans Pharmacogenetics
ISSN:	1532-6535, 1532-6535
Online Access:	Get more information
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