Acute-on-Chronic Liver Failure Clinical Guidelines

In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging as a major cause of mortality. These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of th...

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Vydáno v:The American journal of gastroenterology Ročník 117; číslo 2; s. 225 - 252
Hlavní autoři: Bajaj, Jasmohan S., O'Leary, Jacqueline G., Lai, Jennifer C., Wong, Florence, Long, Millie D., Wong, Robert J., Kamath, Patrick S.
Médium: Journal Article
Jazyk:angličtina
Vydáno: United States Wolters Kluwer 01.02.2022
Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
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ISSN:0002-9270, 1572-0241, 1572-0241
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Abstract In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging as a major cause of mortality. These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations, Assessment, Development, and Evaluation, but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not only, approach to clinical scenarios.
AbstractList In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging as a major cause of mortality. These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations, Assessment, Development, and Evaluation, but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not only, approach to clinical scenarios.
In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging as a major cause of mortality. These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations, Assessment, Development, and Evaluation, but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not only, approach to clinical scenarios.In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging as a major cause of mortality. These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence for these guidelines was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation process. In instances where the evidence was not appropriate for Grading of Recommendations, Assessment, Development, and Evaluation, but there was consensus of significant clinical merit, key concept statements were developed using expert consensus. These guidelines are meant to be broadly applicable and should be viewed as the preferred, but not only, approach to clinical scenarios.
Author Wong, Florence
O'Leary, Jacqueline G.
Long, Millie D.
Bajaj, Jasmohan S.
Kamath, Patrick S.
Wong, Robert J.
Lai, Jennifer C.
AuthorAffiliation Virginia Commonwealth University and Central Virginia Veterans Health Care System, Richmond, Virginia, USA
Dallas Veterans Medical Center and University of Texas Southwestern, Dallas, Texas, USA
University of California San Francisco, San Francisco, California, USA
Mayo Clinic School of Medicine and Science, Rochester, Minnesota, USA
Veterans Affairs Palo Alto Health Care System and Stanford University School of Medicine, Palo Alto, California, USA
University of Toronto, Toronto, Ontario, Canada
Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA
AuthorAffiliation_xml – name: Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA
– name: Dallas Veterans Medical Center and University of Texas Southwestern, Dallas, Texas, USA
– name: University of California San Francisco, San Francisco, California, USA
– name: Mayo Clinic School of Medicine and Science, Rochester, Minnesota, USA
– name: Virginia Commonwealth University and Central Virginia Veterans Health Care System, Richmond, Virginia, USA
– name: Veterans Affairs Palo Alto Health Care System and Stanford University School of Medicine, Palo Alto, California, USA
– name: University of Toronto, Toronto, Ontario, Canada
Author_xml – sequence: 1
  givenname: Jasmohan S.
  surname: Bajaj
  fullname: Bajaj, Jasmohan S.
  organization: Virginia Commonwealth University and Central Virginia Veterans Health Care System, Richmond, Virginia, USA
– sequence: 2
  givenname: Jacqueline G.
  surname: O'Leary
  fullname: O'Leary, Jacqueline G.
  organization: Dallas Veterans Medical Center and University of Texas Southwestern, Dallas, Texas, USA
– sequence: 3
  givenname: Jennifer C.
  surname: Lai
  fullname: Lai, Jennifer C.
  organization: University of California San Francisco, San Francisco, California, USA
– sequence: 4
  givenname: Florence
  surname: Wong
  fullname: Wong, Florence
  organization: University of Toronto, Toronto, Ontario, Canada
– sequence: 5
  givenname: Millie D.
  surname: Long
  fullname: Long, Millie D.
  organization: Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA
– sequence: 6
  givenname: Robert J.
  surname: Wong
  fullname: Wong, Robert J.
  organization: Veterans Affairs Palo Alto Health Care System and Stanford University School of Medicine, Palo Alto, California, USA
– sequence: 7
  givenname: Patrick S.
  surname: Kamath
  fullname: Kamath, Patrick S.
  organization: Mayo Clinic School of Medicine and Science, Rochester, Minnesota, USA
BackLink https://www.ncbi.nlm.nih.gov/pubmed/35006099$$D View this record in MEDLINE/PubMed
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Copyright © 2022 by The American College of Gastroenterology.
2022 by The American College of Gastroenterology
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– reference: 37124683 - Hepatobiliary Surg Nutr. 2023 Apr 10;12(2):239-243
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Snippet In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging as a major cause of mortality. These guidelines indicate the...
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SubjectTerms Acute-On-Chronic Liver Failure - epidemiology
Acute-On-Chronic Liver Failure - therapy
Alcohol
Ascites
Consensus
Disease Management
Gastroenterology
Global Health
Hepatitis
Humans
Intensive care
Liver cirrhosis
Liver diseases
Liver failure
Morbidity - trends
Mortality
Palliative care
Pathophysiology
Patients
Practice Guidelines as Topic
Societies, Medical
Survival Rate - trends
Title Acute-on-Chronic Liver Failure Clinical Guidelines
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Volume 117
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