Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse

T cells are the central drivers of many inflammatory diseases, but the repertoire of tissue-resident T cells at sites of pathology in human organs remains poorly understood. We examined the site-specificity of T cell receptor (TCR) repertoires across tissues (5 to 18 tissues per patient) in prospect...

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Veröffentlicht in:	Science translational medicine Jg. 15; H. 706; S. eabq0476
Hauptverfasser:	DeWolf, Susan, Elhanati, Yuval, Nichols, Katherine, Waters, Nicholas R, Nguyen, Chi L, Slingerland, John B, Rodriguez, Natasia, Lyudovyk, Olga, Giardina, Paul A, Kousa, Anastasia I, Andrlová, Hana, Ceglia, Nick, Fei, Teng, Kappagantula, Rajya, Li, Yanyun, Aleynick, Nathan, Baez, Priscilla, Murali, Rajmohan, Hayashi, Akimasa, Lee, Nicole, Gipson, Brianna, Rangesa, Madhumitha, Katsamakis, Zoe, Dai, Anqi, Blouin, Amanda G, Arcila, Maria, Masilionis, Ignas, Chaligne, Ronan, Ponce, Doris M, Landau, Heather J, Politikos, Ioannis, Tamari, Roni, Hanash, Alan M, Jenq, Robert R, Giralt, Sergio A, Markey, Kate A, Zhang, Yanming, Perales, Miguel-Angel, Socci, Nicholas D, Greenbaum, Benjamin D, Iacobuzio-Donahue, Christine A, Hollmann, Travis J, van den Brink, Marcel R M, Peled, Jonathan U
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 26.07.2023
Schlagworte:	Animals Graft vs Host Disease - pathology Hematopoietic Stem Cell Transplantation Humans Mice Receptors, Antigen, T-Cell T-Lymphocytes - pathology
ISSN:	1946-6242, 1946-6242
Online-Zugang:	Weitere Angaben
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