Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse

T cells are the central drivers of many inflammatory diseases, but the repertoire of tissue-resident T cells at sites of pathology in human organs remains poorly understood. We examined the site-specificity of T cell receptor (TCR) repertoires across tissues (5 to 18 tissues per patient) in prospect...

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Vydáno v:	Science translational medicine Ročník 15; číslo 706; s. eabq0476
Hlavní autoři:	DeWolf, Susan, Elhanati, Yuval, Nichols, Katherine, Waters, Nicholas R, Nguyen, Chi L, Slingerland, John B, Rodriguez, Natasia, Lyudovyk, Olga, Giardina, Paul A, Kousa, Anastasia I, Andrlová, Hana, Ceglia, Nick, Fei, Teng, Kappagantula, Rajya, Li, Yanyun, Aleynick, Nathan, Baez, Priscilla, Murali, Rajmohan, Hayashi, Akimasa, Lee, Nicole, Gipson, Brianna, Rangesa, Madhumitha, Katsamakis, Zoe, Dai, Anqi, Blouin, Amanda G, Arcila, Maria, Masilionis, Ignas, Chaligne, Ronan, Ponce, Doris M, Landau, Heather J, Politikos, Ioannis, Tamari, Roni, Hanash, Alan M, Jenq, Robert R, Giralt, Sergio A, Markey, Kate A, Zhang, Yanming, Perales, Miguel-Angel, Socci, Nicholas D, Greenbaum, Benjamin D, Iacobuzio-Donahue, Christine A, Hollmann, Travis J, van den Brink, Marcel R M, Peled, Jonathan U
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 26.07.2023
Témata:	Animals Graft vs Host Disease - pathology Hematopoietic Stem Cell Transplantation Humans Mice Receptors, Antigen, T-Cell T-Lymphocytes - pathology
ISSN:	1946-6242, 1946-6242
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