Fully Automatic Scar Segmentation for Late Gadolinium Enhancement MRI Images in Left Ventricle with Myocardial Infarction

Summary Numerous methods have been published to segment the infarct tissue in the left ventricle, most of them either need manual work, post-processing, or suffer from poor reproducibility. We proposed an automatic segmentation method for segmenting the infarct tissue in left ventricle with myocardi...

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Bibliographic Details
Published in:Current medical science Vol. 41; no. 2; pp. 398 - 404
Main Authors: Wu, Zheng-hong, Sun, Li-ping, Liu, Yun-long, Dong, Dian-dian, Tong, Lv, Deng, Dong-dong, He, Yi, Wang, Hui, Sun, Yi-bo, Dong, Jian-zeng, Xia, Ling
Format: Journal Article
Language:English
Published: Wuhan Huazhong University of Science and Technology 01.04.2021
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ISSN:2096-5230, 2523-899X, 2523-899X
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Summary:Summary Numerous methods have been published to segment the infarct tissue in the left ventricle, most of them either need manual work, post-processing, or suffer from poor reproducibility. We proposed an automatic segmentation method for segmenting the infarct tissue in left ventricle with myocardial infarction. Cardiac images of a total of 60 diseased hearts (55 human hearts and 5 porcine hearts) were used in this study. The epicardial and endocardial boundaries of the ventricles in every 2D slice of the cardiac magnetic resonance with late gadolinium enhancement images were manually segmented. The subsequent pipeline of infarct tissue segmentation is fully automatic. The segmentation results with the automatic algorithm proposed in this paper were compared to the consensus ground truth. The median of Dice overlap between our automatic method and the consensus ground truth is 0.79. We also compared the automatic method with the consensus ground truth using different image sources from different centers with different scan parameters and different scan machines. The results showed that the Dice overlap with the public dataset was 0.83, and the overall Dice overlap was 0.79. The results show that our method is robust with respect to different MRI image sources, which were scanned by different centers with different image collection parameters. The segmentation accuracy we obtained is comparable to or better than that of the conventional semi-automatic methods. Our segmentation method may be useful for processing large amount of dataset in clinic.
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ISSN:2096-5230
2523-899X
2523-899X
DOI:10.1007/s11596-021-2360-z