Traditionally living populations in East Africa have a mean serum 25-hydroxyvitamin D concentration of 115 nmol/l

Cutaneous synthesis of vitamin D by exposure to UVB is the principal source of vitamin D in the human body. Our current clothing habits and reduced time spent outdoors put us at risk of many insufficiency-related diseases that are associated with calcaemic and non-calcaemic functions of vitamin D. P...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	British journal of nutrition Ročník 108; číslo 9; s. 1557 - 1561
Hlavní autoři:	Luxwolda, Martine F., Kuipers, Remko S., Kema, Ido P., Janneke Dijck-Brouwer, D. A., Muskiet, Frits A. J.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Cambridge, UK Cambridge University Press 14.11.2012
Témata:	25-Hydroxyvitamin D 2 - blood Adolescent Adult African Continental Ancestry Group Aged blood serum body mass index Calcifediol - blood calcium Developing Countries direct contact Female Homeostasis Humans Life Style - ethnology lifestyle Liquid chromatography Male males Middle Aged Nutrition research Nutritional Requirements people risk Rural Health - ethnology Short Communication Skin Pigmentation solar radiation Sunlight Tanzania Tanzania - epidemiology Vitamin D Vitamin D Deficiency - blood Vitamin D Deficiency - epidemiology Vitamin D Deficiency - ethnology Vitamin D Deficiency - prevention & control vitamin status Young Adult Tanzania East Africa Evolution Hadzabe Maasai 25-Hydroxyvitamin D
ISSN:	0007-1145, 1475-2662, 1475-2662
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Popis
Shrnutí:	Cutaneous synthesis of vitamin D by exposure to UVB is the principal source of vitamin D in the human body. Our current clothing habits and reduced time spent outdoors put us at risk of many insufficiency-related diseases that are associated with calcaemic and non-calcaemic functions of vitamin D. Populations with traditional lifestyles having lifelong, year-round exposure to tropical sunlight might provide us with information on optimal vitamin D status from an evolutionary perspective. We measured the sum of serum 25-hydroxyvitamin D2 and D3 (25(OH)D) concentrations of thirty-five pastoral Maasai (34 (sd 10) years, 43 % male) and twenty-five Hadzabe hunter–gatherers (35 (sd 12) years, 84 % male) living in Tanzania. They have skin type VI, have a moderate degree of clothing, spend the major part of the day outdoors, but avoid direct exposure to sunlight when possible. Their 25(OH)D concentrations were measured by liquid chromatography–MS/MS. The mean serum 25(OH)D concentrations of Maasai and Hadzabe were 119 (range 58–167) and 109 (range 71–171) nmol/l, respectively. These concentrations were not related to age, sex or BMI. People with traditional lifestyles, living in the cradle of mankind, have a mean circulating 25(OH)D concentration of 115 nmol/l. Whether this concentration is optimal under the conditions of the current Western lifestyle is uncertain, and should as a possible target be investigated with concomitant appreciation of other important factors in Ca homeostasis that we have changed since the agricultural revolution.
Bibliografie:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 14 ObjectType-Article-1 ObjectType-Feature-2 content type line 23
ISSN:	0007-1145 1475-2662 1475-2662
DOI:	10.1017/S0007114511007161