Fifty years of paracetamol (acetaminophen) poisoning: the development of risk assessment and treatment 1973–2023 with particular focus on contributions published from Edinburgh and Denver

Fifty years ago, basic scientific studies and the availability of assay methods made the assessment of risk in paracetamol (acetaminophen) poisoning possible. The use of the antidote acetylcysteine linked to new methods of risk assessment transformed the treatment of this poisoning. This review will...

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Bibliographic Details
Published in:	Clinical toxicology (Philadelphia, Pa.) Vol. 61; no. 12; pp. 1020 - 1031
Main Authors:	Bateman, D. Nicholas, Dart, Richard C., Dear, James W., Prescott, Laurie F., Rumack, Barry H.
Format:	Journal Article
Language:	English
Published:	England 02.12.2023
Subjects:	Acetaminophen Acetylcysteine - therapeutic use Analgesics, Non-Narcotic Antidotes - therapeutic use Antiemetics - therapeutic use Chemical and Drug Induced Liver Injury - diagnosis Chemical and Drug Induced Liver Injury - epidemiology Chemical and Drug Induced Liver Injury - etiology Drug Overdose - diagnosis Drug Overdose - drug therapy Humans Multicenter Studies as Topic Risk Assessment poisons management acetylcysteine antidotes risk assessment Paracetamol
ISSN:	1556-3650, 1556-9519, 1556-9519
Online Access:	Get full text
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