PRAME immunohistochemistry in soft tissue tumors and mimics: a study of 350 cases highlighting its imperfect specificity but potentially useful diagnostic applications

Preferentially expressed antigen in melanoma (PRAME) immunohistochemistry is currently used in pathology for the assessment of melanocytic neoplasms; however, knowledge of its expression patterns in soft tissue tumors is limited. PRAME immunohistochemistry (clone QR005) was assessed on whole tissue...

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Bibliographic Details
Published in:	Virchows Archiv : an international journal of pathology Vol. 483; no. 2; pp. 145 - 156
Main Authors:	Cammareri, Chloé, Beltzung, Fanny, Michal, Michael, Vanhersecke, Lucile, Coindre, Jean-Michel, Velasco, Valérie, Le Loarer, François, Vergier, Béatrice, Perret, Raul
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2023 Springer Nature B.V
Subjects:	Adult Alveoli Antigens Antigens, Neoplasm Biomarkers, Tumor - metabolism Chondrosarcoma Dermatofibrosarcoma protuberans Diagnosis, Differential Diagnostic software DNA Helicases Ewing's sarcoma Ewings sarcoma Extraskeletal myxoid chondrosarcoma Fasciitis Fibrosarcoma - diagnosis Head & neck cancer Hemangioma Histiocytoma Humans Hyperplasia Immunohistochemistry Inflammation Lesions Lipoma Liposarcoma Lymphangioma Malignancy Medical diagnosis Medicine Medicine & Public Health Melanoma Melanoma - pathology Neoplasms Nuclear Proteins Original Article Pathology Peripheral nerves Rhabdomyosarcoma Sarcoma Sarcoma - diagnosis Sarcoma - pathology Sarcoma, Ewing - diagnosis Schwann cells Sheaths Skin Neoplasms - pathology Soft Tissue Neoplasms - diagnosis Soft Tissue Neoplasms - pathology Soft tissues Synovial sarcoma Thorax Tissues Transcription Factors Tumors Immunohistochemistry Sarcoma Immunotherapy Melanoma PRAME Soft tissue Differential diagnosis
ISSN:	0945-6317, 1432-2307, 1432-2307
Online Access:	Get full text
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