Opioid-Induced Tolerance and Hyperalgesia

Opioids are very potent and efficacious drugs, traditionally used for both acute and chronic pain conditions. However, the use of opioids is frequently associated with the occurrence of adverse effects or clinical problems. Other than adverse effects and dependence, the development of tolerance is a...

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Bibliographic Details
Published in:	CNS drugs Vol. 33; no. 10; pp. 943 - 955
Main Authors:	Mercadante, Sebastiano, Arcuri, Edoardo, Santoni, Angela
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01.10.2019 Springer Nature B.V
Subjects:	Adaptation Analgesia Analgesics Anesthetics Chronic pain Current Opinion Drug dosages Drug tolerance Drug withdrawal Hyperalgesia Hypersensitivity Local anesthetics Medicine Medicine & Public Health Morphine Mortality Narcotics Neurology Neurosciences Opioids Pain Pain perception Patients Pharmacotherapy Psychiatry Psychopharmacology Side effects Substance abuse treatment
ISSN:	1172-7047, 1179-1934, 1179-1934
Online Access:	Get full text
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