The Landmark Series: Breast Conservation Trials (including oncoplastic breast surgery)

Significant progress has been made in the treatment and outcome of breast cancer. Some of the most dramatic strides have been in the surgical management of breast cancer. Breast-conserving therapy (BCT), including wide local excision of the tumor followed by irradiation, has become a standard treatm...

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Bibliographic Details
Published in:Annals of surgical oncology Vol. 28; no. 4; pp. 2120 - 2127
Main Authors: Margenthaler, Julie A., Dietz, Jill R., Chatterjee, Abhishek
Format: Journal Article
Language:English
Published: Cham Springer International Publishing 01.04.2021
Springer Nature B.V
Subjects:
Breast
Breast cancer
Breast Neoplasms - surgery
Breast Oncology
Breast surgery
Clinical trials
Female
Humans
Invasiveness
Mastectomy
Mastectomy, Segmental
Medicine
Medicine & Public Health
Oncology
Surgery
Surgical Oncology
ISSN:1068-9265, 1534-4681, 1534-4681
Online Access:Get full text
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Summary:Significant progress has been made in the treatment and outcome of breast cancer. Some of the most dramatic strides have been in the surgical management of breast cancer. Breast-conserving therapy (BCT), including wide local excision of the tumor followed by irradiation, has become a standard treatment option for women with early-stage invasive breast cancer. Large cooperative group trials have contributed to the paradigm shift from mastectomy to BCT. This review reports the landmark BCT trials that provided the data for current surgical practices. The review also describes the body of literature contributing to the increasing use of oncoplastic techniques for patients undergoing BCT.
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ISSN:1068-9265
1534-4681
1534-4681
DOI:10.1245/s10434-020-09534-y