Combination of “quadratic adaptive algorithm” and “hybrid operator splitting” or uniformization algorithms for stability against acceleration in the Markov model of sodium ion channels in the ventricular cell model

The Markovian model has generally been used for cardiac electrophysiological simulations. However, the Markovian model is so stiff that speeding up the computation of the algorithms with variable time-steps always results in simulation instability. In particular, the unstable simulations always occu...

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Vydané v:	Medical & biological engineering & computing Ročník 57; číslo 6; s. 1367 - 1379
Hlavní autori:	Chen, Xing-Ji, Luo, Ching-Hsing, Chen, Min-Hung, Zhou, Xiang
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2019 Springer Nature B.V
Predmet:	Acceleration Adaptive algorithms Algorithms Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Computation Computer Applications Computer simulation Human Physiology Imaging Ion channels Low voltage Markov analysis Markov chains Original Article Radiology Simulation Sodium Sodium channels Splitting Stability Ventricle Ventricular cell model Action potential Computer simulation Adaptive algorithm Markovian model of sodium channel
ISSN:	0140-0118, 1741-0444, 1741-0444
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