Volcano plots in analyzing differential expressions with mRNA microarrays

A volcano plot displays unstandardized signal (e.g. log-fold-change) against noise-adjusted/standardized signal (e.g. t-statistic or -log(10)(p-value) from the t-test). We review the basic and interactive use of the volcano plot and its crucial role in understanding the regularized t-statistic. The...

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Bibliographic Details

Published in:	Journal of bioinformatics and computational biology Vol. 10; no. 6; p. 1231003
Main Author:	Li, Wentian
Format:	Journal Article
Language:	English
Published:	Singapore 01.12.2012
Subjects:	Animals Gene Expression Profiling - methods Humans Models, Statistical Oligonucleotide Array Sequence Analysis - methods Oligonucleotide Array Sequence Analysis - statistics & numerical data RNA, Messenger - genetics RNA, Messenger - metabolism Software
ISSN:	1757-6334, 1757-6334
Online Access:	Get more information
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