Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions. There will be an estimated 1...

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Published in:CA: a cancer journal for clinicians Vol. 68; no. 6; pp. 394 - 424
Main Authors: Bray, Freddie, Ferlay, Jacques, Soerjomataram, Isabelle, Siegel, Rebecca L., Torre, Lindsey A., Jemal, Ahmedin
Format: Journal Article
Language:English
Published: United States Wiley Subscription Services, Inc 01.11.2018
Subjects:
Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Breast cancer
Cancer
Cause of Death - trends
Cervical cancer
Cervix
Child
Child, Preschool
Colorectal cancer
Colorectal carcinoma
Control programs
Death
Economic development
Epidemiology
Female
Gastric cancer
Global Burden of Disease - statistics & numerical data
Global Health - statistics & numerical data
Humans
Incidence
Infant
Infant, Newborn
Liver cancer
Lung cancer
Male
Middle Aged
Mortality
Neoplasms - epidemiology
Prevalence
Prostate cancer
Registries - statistics & numerical data
Risk Factors
Sex Distribution
Skin cancer
Stomach
survival
Survival Rate
Young Adult
epidemiology
cancer
incidence
survival
ISSN:0007-9235, 1542-4863, 1542-4863
Online Access:Get full text
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Summary:This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions. There will be an estimated 18.1 million new cancer cases (17.0 million excluding nonmelanoma skin cancer) and 9.6 million cancer deaths (9.5 million excluding nonmelanoma skin cancer) in 2018. In both sexes combined, lung cancer is the most commonly diagnosed cancer (11.6% of the total cases) and the leading cause of cancer death (18.4% of the total cancer deaths), closely followed by female breast cancer (11.6%), prostate cancer (7.1%), and colorectal cancer (6.1%) for incidence and colorectal cancer (9.2%), stomach cancer (8.2%), and liver cancer (8.2%) for mortality. Lung cancer is the most frequent cancer and the leading cause of cancer death among males, followed by prostate and colorectal cancer (for incidence) and liver and stomach cancer (for mortality). Among females, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death, followed by colorectal and lung cancer (for incidence), and vice versa (for mortality); cervical cancer ranks fourth for both incidence and mortality. The most frequently diagnosed cancer and the leading cause of cancer death, however, substantially vary across countries and within each country depending on the degree of economic development and associated social and life style factors. It is noteworthy that high‐quality cancer registry data, the basis for planning and implementing evidence‐based cancer control programs, are not available in most low‐ and middle‐income countries. The Global Initiative for Cancer Registry Development is an international partnership that supports better estimation, as well as the collection and use of local data, to prioritize and evaluate national cancer control efforts. CA: A Cancer Journal for Clinicians 2018;0:1‐31. © 2018 American Cancer Society
Bibliography:DISCLOSURES:Lindsey A. Torre, Ahmedin Jemal, and Rebecca L. Siegel are employed by the American Cancer Society, which received a grant from Merck Inc for intramural research outside the submitted work; however, their salaries are solely funded through American Cancer Society funds. The remaining authors report no conflicts of interest.
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ISSN:0007-9235
1542-4863
1542-4863
DOI:10.3322/caac.21492