Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling

Glioblastoma ranks among the most aggressive and lethal of all human cancers. Functionally defined glioma stem cells (GSC) contribute to this poor prognosis by driving therapeutic resistance and maintaining cellular heterogeneity. To understand the molecular processes essential for GSC maintenance a...

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Vydané v:	Cancer discovery Ročník 9; číslo 9; s. 1248
Hlavní autori:	Gimple, Ryan C, Kidwell, Reilly L, Kim, Leo J Y, Sun, Tengqian, Gromovsky, Anthony D, Wu, Qiulian, Wolf, Megan, Lv, Deguan, Bhargava, Shruti, Jiang, Li, Prager, Briana C, Wang, Xiuxing, Ye, Qing, Zhu, Zhe, Zhang, Guoxin, Dong, Zhen, Zhao, Linjie, Lee, Derrick, Bi, Junfeng, Sloan, Andrew E, Mischel, Paul S, Brown, J Mark, Cang, Hu, Huan, Tao, Mack, Stephen C, Xie, Qi, Rich, Jeremy N
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.09.2019
ISSN:	2159-8290, 2159-8290
On-line prístup:	Zistit podrobnosti o prístupe
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