Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling

Glioblastoma ranks among the most aggressive and lethal of all human cancers. Functionally defined glioma stem cells (GSC) contribute to this poor prognosis by driving therapeutic resistance and maintaining cellular heterogeneity. To understand the molecular processes essential for GSC maintenance a...

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Veröffentlicht in:	Cancer discovery Jg. 9; H. 9; S. 1248
Hauptverfasser:	Gimple, Ryan C, Kidwell, Reilly L, Kim, Leo J Y, Sun, Tengqian, Gromovsky, Anthony D, Wu, Qiulian, Wolf, Megan, Lv, Deguan, Bhargava, Shruti, Jiang, Li, Prager, Briana C, Wang, Xiuxing, Ye, Qing, Zhu, Zhe, Zhang, Guoxin, Dong, Zhen, Zhao, Linjie, Lee, Derrick, Bi, Junfeng, Sloan, Andrew E, Mischel, Paul S, Brown, J Mark, Cang, Hu, Huan, Tao, Mack, Stephen C, Xie, Qi, Rich, Jeremy N
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.09.2019
ISSN:	2159-8290, 2159-8290
Online-Zugang:	Weitere Angaben
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