Intrachiasmatic abscess caused by IgG4-related hypophysitis

Introduction Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported. Methods In this study, we report a case of a 29-year-old female with bite...

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Vydáno v:	Acta neurochirurgica Ročník 159; číslo 11; s. 2229 - 2233
Hlavní autoři:	Hadjigeorgiou, Georgios F., Lund, Eva Løbner, Poulsgaard, Lars, Feldt-Rasmussen, Ulla, Rasmussen, Åse Krogh, Wegener, Marianne, Fugleholm, Kåre
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Vienna Springer Vienna 01.11.2017 Springer Nature B.V
Témata:	Adult Autoimmune Hypophysitis - complications Autoimmune Hypophysitis - diagnostic imaging Autoimmune Hypophysitis - pathology Autoimmune Hypophysitis - surgery Brain Abscess - complications Brain Abscess - diagnostic imaging Brain Abscess - pathology Brain Abscess - surgery Case Report - Brain Tumors Case reports Compression Decompression Decompression, Surgical Female Hemianopsia - etiology Humans Immunoglobulin G Interventional Radiology Magnetic Resonance Imaging Medicine Medicine & Public Health Minimally Invasive Surgery Neurology Neuroradiology Neurosurgery Neurosurgical Procedures Optic chiasm Optic Chiasm - diagnostic imaging Optic Chiasm - surgery Pituitary Rare diseases Surgical Orthopedics Vision IgG4 Intrachiasmatic Abscess Hypophysitis
ISSN:	0001-6268, 0942-0940, 0942-0940
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Shrnutí:	Introduction Autoimmune hypophysitis is a rare disease of the pituitary, which may affect vision by inflammation and compression of the optic chiasm. However, intrachiasmatic abscess formation has not been previously reported. Methods In this study, we report a case of a 29-year-old female with bitemporal hemianopia due to a cystic intrasellar tumor. The patient underwent surgical decompression of the lesion, which was found to be an intrachiasmatic abscess. Results The histologic findings were consistent with IgG4 hypophysitis. Conclusion This rare clinical presentation suggests that in case of a disproportionate degree of visual impairment in relation to the size of the lesion, suspicion should lead to an intrachiasmatic lesion.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Case Study-2 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0001-6268 0942-0940 0942-0940
DOI:	10.1007/s00701-017-3288-8