Optical Imaging Modalities: Principles and Applications in Preclinical Research and Clinical Settings

With the ability to noninvasively image and monitor molecular processes within tumors, molecular imaging represents a fundamental tool for cancer scientists. In the current review, we describe emergent optical technologies for molecular imaging. We aim to provide the reader with an overview of the f...

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Bibliographic Details
Published in:The Journal of nuclear medicine (1978) Vol. 61; no. 10; p. 1419
Main Authors: Pirovano, Giacomo, Roberts, Sheryl, Kossatz, Susanne, Reiner, Thomas
Format: Journal Article
Language:English
Published: United States 01.10.2020
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ISSN:1535-5667, 1535-5667
Online Access:Get more information
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Summary:With the ability to noninvasively image and monitor molecular processes within tumors, molecular imaging represents a fundamental tool for cancer scientists. In the current review, we describe emergent optical technologies for molecular imaging. We aim to provide the reader with an overview of the fundamental principles on which each imaging strategy is based, to introduce established and future applications, and to provide a rationale for selecting optical technologies for molecular imaging depending on disease location, biology, and anatomy. To accelerate clinical translation of imaging techniques, we also describe examples of practical applications in patients. Elevating these techniques into standard-of-care tools will transform patient stratification, disease monitoring, and response evaluation.
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ISSN:1535-5667
1535-5667
DOI:10.2967/jnumed.119.238279