Optical Imaging Modalities: Principles and Applications in Preclinical Research and Clinical Settings

With the ability to noninvasively image and monitor molecular processes within tumors, molecular imaging represents a fundamental tool for cancer scientists. In the current review, we describe emergent optical technologies for molecular imaging. We aim to provide the reader with an overview of the f...

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Vydané v:The Journal of nuclear medicine (1978) Ročník 61; číslo 10; s. 1419
Hlavní autori: Pirovano, Giacomo, Roberts, Sheryl, Kossatz, Susanne, Reiner, Thomas
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 01.10.2020
Predmet:
Humans
Luminescent Measurements - methods
Microscopy, Fluorescence
Molecular Imaging - methods
Neoplasms - diagnostic imaging
Optical Imaging - methods
Photoacoustic Techniques - methods
Standard of Care
imaging
cancer
optical modalities
ISSN:1535-5667, 1535-5667
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Shrnutí:With the ability to noninvasively image and monitor molecular processes within tumors, molecular imaging represents a fundamental tool for cancer scientists. In the current review, we describe emergent optical technologies for molecular imaging. We aim to provide the reader with an overview of the fundamental principles on which each imaging strategy is based, to introduce established and future applications, and to provide a rationale for selecting optical technologies for molecular imaging depending on disease location, biology, and anatomy. To accelerate clinical translation of imaging techniques, we also describe examples of practical applications in patients. Elevating these techniques into standard-of-care tools will transform patient stratification, disease monitoring, and response evaluation.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:1535-5667
1535-5667
DOI:10.2967/jnumed.119.238279