Multiple Sequence Alignment as a Facility-Location Problem

A connection is made between certain multiple-sequence alignment problems and facility-location problems, and the existence of a PTAS (polynomial-time approximation scheme) for these problems is shown. Moreover, it is shown that multiple sequence alignment with SP-score and fixed gap penalties is MA...

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Veröffentlicht in:INFORMS journal on computing Jg. 16; H. 4; S. 430 - 440
Hauptverfasser: Just, Winfried, Vedova, Gianluca Della
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Linthicum INFORMS 01.11.2004
Institute for Operations Research and the Management Sciences
Schlagworte:
Algorithms
analysis of algorithms: computational complexity
Computer science
Correlation analysis
facilities-equipment planning: location
Studies
ISSN:1091-9856, 1526-5528, 1091-9856
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Abstract A connection is made between certain multiple-sequence alignment problems and facility-location problems, and the existence of a PTAS (polynomial-time approximation scheme) for these problems is shown. Moreover, it is shown that multiple sequence alignment with SP-score and fixed gap penalties is MAX SNP-hard.
AbstractList A connection is made between certain multiple-sequence alignment problems and facility-location problems, and the existence of a PTAS (polynomial-time approximation scheme) for these problems is shown. Moreover, it is shown that multiple sequence alignment with SP-score and fixed gap penalties is MAX SNP-hard.
A connection is made between certain multiple-sequence alignment problems and facility-location problems, and the existence of a PTAS (polynomial-time approximation scheme) for these problems is shown. Moreover, it is shown that multiple sequence alignment with SP-score and fixed gap penalties is MAX SNP-hard. [PUBLICATION ABSTRACT]
Audience Academic
Author Just, Winfried
Vedova, Gianluca Della
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10.1006/jcss.1998.1605
10.1016/S0304-3975(02)00439-5
10.1002/1097-0037(200010)36:3<147::AID-NET1>3.0.CO;2-M
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10.1089/106652701753307511
10.1016/S0304-3975(99)00324-2
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10.1007/3-540-62592-5_80
10.1007/978-3-540-24587-2_37
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10.1006/jcss.2002.1823
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Snippet A connection is made between certain multiple-sequence alignment problems and facility-location problems, and the existence of a PTAS (polynomial-time...
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SubjectTerms Algorithms
analysis of algorithms: computational complexity
Computer science
Correlation analysis
facilities-equipment planning: location
Studies
Title Multiple Sequence Alignment as a Facility-Location Problem
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