Epidemiology of endometriosis: a large population‐based database study from a healthcare provider with 2 million members

Objective Endometriosis constitutes a significant burden on the quality of life of women, their families and healthcare systems. The objective of this study is to describe the real‐world epidemiology of endometriosis in an unselected low‐risk population in Israel. Design Retrospective population‐bas...

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Published in:BJOG : an international journal of obstetrics and gynaecology Vol. 125; no. 1; pp. 55 - 62
Main Authors: Eisenberg, VH, Weil, C, Chodick, G, Shalev, V
Format: Journal Article
Language:English
Published: England Wiley Subscription Services, Inc 01.01.2018
Subjects:
Adolescent
Adult
Age Distribution
Chronic illnesses
Diagnosis
Endometriosis
Endometriosis - epidemiology
Epidemiology
Female
Humans
Incidence
Infertility
Infertility, Female - epidemiology
Israel - epidemiology
Middle Aged
Multiple Chronic Conditions - epidemiology
Patient Acceptance of Health Care - statistics & numerical data
Population studies
Population-based studies
Prevalence
Quality of life
Residence Characteristics - statistics & numerical data
Retrospective Studies
Socioeconomic Factors
Young Adult
Israel
endometriosis
epidemiology
prevalence
Diagnosis
ISSN:1470-0328, 1471-0528, 1471-0528
Online Access:Get full text
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Summary:Objective Endometriosis constitutes a significant burden on the quality of life of women, their families and healthcare systems. The objective of this study is to describe the real‐world epidemiology of endometriosis in an unselected low‐risk population in Israel. Design Retrospective population‐based study. Setting and sample The computerised databases of Maccabi Healthcare Services (MHS), a 2‐million‐member healthcare provider representing a quarter of the Israeli population. Methods The crude point prevalence (31 December 2015; diagnosed since 1998) and annual incidence (2000–2015) rates of diagnosed endometriosis (ICD‐9‐CM 617.xx) were assessed among women aged 15–55 years. Prevalent patients were characterised in terms of sociodemographic and clinical characteristics, including validated MHS infertility and chronic disease registries. Main outcome measures Prevalence and incidence of diagnosed endometriosis in MHS. Results The point prevalence of endometriosis [n = 6146, mean age 40.4 ± 8.0 years (SD)] was 10.8 per 1000 (95% CI 10.5–11.0). Women aged 40–44 years had the highest prevalence rate of 18.6 per 1000 (95% CI 17.7–19.5). Infertility was documented in 37% of patients. A total of 6045 patients were included in the cohort of newly‐diagnosed endometriosis (mean age 34.0 ± 8.1 years), corresponding to an average annual incidence rate of 7.2 per 10 000 (95% CI 6.5–8.0). Conclusions We observed a substantially lower prevalence of diagnosed endometriosis compared with previous reports in high‐risk populations, in line with population‐based estimates from European databases (range 0.8–1.8%). Further characterisation of this cohort may help to understand what affects the prevalence of endometriosis in Israel, and to promote earlier diagnosis and improve management in clinical practice. Tweetable Endometriosis diagnosed in 1% of women, according to a large population‐based study in a community setting. Tweetable Endometriosis diagnosed in 1% of women, according to a large population‐based study in a community setting.
Bibliography:This article is commented on by LR Goodman and JM Franasiak, p. 63 in this issue. To view this mini commentary visit
https://doi.org/10.1111/1471-0528.14701
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ISSN:1470-0328
1471-0528
1471-0528
DOI:10.1111/1471-0528.14711