Endotoxin-polluted medium in a human in vitro fertilization program

Optimal quality control measures to obtain the highest possible success rate for an in vitro fertilization and embryo transfer program is important in any program. Poor results obtained during a cycle where no pregnancies were achieved necessitated an investigation into possible causes. A suspected...

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Vydané v:Fertility and sterility Ročník 46; číslo 2; s. 273
Hlavní autori: Snyman, E, Van der Merwe, J V
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 01.08.1986
Predmet:
Culture Media - standards
Embryo, Mammalian - drug effects
Endotoxins - adverse effects
Female
Fertilization in Vitro - methods
Humans
Oocytes - drug effects
Pregnancy
Water
ISSN:0015-0282
On-line prístup:Zistit podrobnosti o prístupe
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Popis
Shrnutí:Optimal quality control measures to obtain the highest possible success rate for an in vitro fertilization and embryo transfer program is important in any program. Poor results obtained during a cycle where no pregnancies were achieved necessitated an investigation into possible causes. A suspected contamination of the multidistilled water utilized in medium preparation was confirmed. During a successful cycle with no endotoxins present, a pregnancy rate of 27.2% was achieved. This is higher than the 6.3% pregnancy rate achieved in another cycle where endotoxins were isolated in the media. This article illustrates cell morphologic and ultrastructural changes which could be ascribed to the presence of these endotoxins.
Bibliografia:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0015-0282
DOI:10.1016/S0015-0282(16)49525-7