The Effects of Angiogenic Growth Factors on Extravillous Trophoblast Invasion and Motility

There is accumulating evidence that deficient trophoblast invasion of the placental bed spiral arteries is crucial to the pathogenesis of pre-eclampsia and intrauterine growth restriction. However, the factors which regulate the process of trophoblast invasion remain unclear. We have investigated wh...

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Bibliographic Details
Published in:	Placenta (Eastbourne) Vol. 20; no. 8; pp. 661 - 667
Main Authors:	Lash, G.E, Cartwright, J.E, Whitley, G.St J, Trew, A.J, Baker, P.N
Format:	Journal Article Conference Proceeding
Language:	English
Published:	Oxford Elsevier Ltd 01.11.1999 Elsevier
Subjects:	Biological and medical sciences Cell Movement - drug effects Cell physiology Cells, Cultured Endothelial Growth Factors - pharmacology Extracellular Matrix - ultrastructure Fundamental and applied biological sciences. Psychology Humans Lymphokines - pharmacology Molecular and cellular biology Placenta Growth Factor Pregnancy Proteins - pharmacology Protein Isoforms - pharmacology Responses to growth factors, tumor promotors, other factors Reverse Transcriptase Polymerase Chain Reaction Trophoblasts - drug effects Trophoblasts - pathology Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors Human Cell proliferation Trophoblaste Motility Fetal membrane Reverse transcription Placental villi In vitro Polymerase chain reaction Vascular endothelium growth factor Established cell line Placenta growth factor Biological receptor
ISSN:	0143-4004, 1532-3102
Online Access:	Get full text
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