Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study

Purpose Detection of specific molecular alterations in tumors guides the selection of effective targeted treatment of patients with several types of cancer. These molecular alterations may occur in other tumor types for which the efficacy of targeted therapy remains unclear. The MyPathway study eval...

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Vydané v:	Journal of clinical oncology Ročník 36; číslo 6; s. 536
Hlavní autori:	Hainsworth, John D, Meric-Bernstam, Funda, Swanton, Charles, Hurwitz, Herbert, Spigel, David R, Sweeney, Christopher, Burris, Howard, Bose, Ron, Yoo, Bongin, Stein, Alisha, Beattie, Mary, Kurzrock, Razelle
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 20.02.2018
Predmet:	Adult Aged Aged, 80 and over ErbB Receptors - antagonists & inhibitors ErbB Receptors - genetics Female Hedgehog Proteins - antagonists & inhibitors Humans Male Middle Aged Molecular Targeted Therapy - methods Mutation Neoplasms - drug therapy Neoplasms - genetics Proto-Oncogene Proteins B-raf - antagonists & inhibitors Proto-Oncogene Proteins B-raf - genetics Receptor, ErbB-2 - antagonists & inhibitors Receptor, ErbB-2 - genetics
ISSN:	1527-7755, 1527-7755
On-line prístup:	Zistit podrobnosti o prístupe
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