Experimental Trypanosoma evansi infection induces pain along with oxidative stress, prevented by COX-2 inhibition

[Display omitted] •Nonsteroidal anti-inflammatory drugs prevent inflammation, pain and oxidative stress triggered by T. evansi rodent infection.•The inflammation provoked by T. evansi infection in probably mediated by cyclooxygenase-2 and its molecular mediators.•Mice infected by T. evansi show high...

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Bibliographic Details

Published in:	Experimental parasitology Vol. 247; p. 108477
Main Authors:	Cipriani, Daniel Sérgio, Borges, Gabriela Kaiser, Povaluk, Ana Paula, Stipp, Maria Carolina, Casagrande, Renata Assis, Vogel, Carla Ivane Ganz, Miletti, Luiz Claudio, Bastos-Pereira, Amanda Leite
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.04.2023
Subjects:	Cyclooxygenase 2 Humans Oxidative Stress Pain Trypanosoma Trypanosomiasis - drug therapy
ISSN:	0014-4894, 1090-2449, 1090-2449
Online Access:	Get full text
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