Rule-based algorithm for the identification of single and binary mixtures of cross-reacting neonicotinoids with microsphere-based immunoassays

Microsphere-based immunoassays are widely used for high-throughput multi-analyte determination. However, as multiple structurally similar analytes often cross-react with the same antibody, identifying which exact (mixture of) cross-reacting analytes is present is not possible in such instances. The...

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Bibliographic Details
Published in:	Talanta (Oxford) Vol. 298; no. Pt B; p. 128947
Main Authors:	Lemmink, Ids B., Alewijn, Martin, Beij, Erik, Xu, Mang, Bovee, Toine F.H., Peters, Jeroen, Salentijn, Gert IJ
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.02.2026
Subjects:	Algorithms Bootstrapping Cross Reactions Cross-reacting analyte identification algorithm Data analysis Immunoassay - methods Microsphere-based immunoassays Microspheres Neonicotinoids - analysis Neonicotinoids - immunology z-score Bootstrapping Microsphere-based immunoassays Data analysis z-score Cross-reacting analyte identification algorithm
ISSN:	0039-9140, 1873-3573, 1873-3573
Online Access:	Get full text
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