BPMambaMIL: A bio-inspired prototype-guided multiple instance learning for oncotype DX risk assessment in histopathology

•BPMambaMIL, a novel prototype-guided model, enhances breast cancer recurrence prediction from pathology images.•Bio-inspired prototype selection effectively captures complex histopathological features.•BPMambaMIL outperforms state-of-the-art models, especially in classifying high-risk Oncotype DX s...

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