A reliable micro-CT-based method reveals dynamic changes to alveolar bone and tooth root following ligature-induced periodontal injury in the mouse

This study presents a method development and evaluation framework for assessing longitudinally the dynamic alveolar bone changes in a murine periodontal injury model using 3D Slicer software. Accurate and reproducible measurement of bone loss is crucial for periodontal research, yet traditional two-...

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Bibliographic Details
Published in:	Bone (New York, N.Y.) Vol. 201; p. 117619
Main Authors:	Fu, Yu, Qayyum, Wasif, Shafiei, Parsa, Eaton, Farah, Alexiou, Maria, Graf, Daniel
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01.12.2025
Subjects:	3D Slicer Alveolar Bone Loss - diagnostic imaging Alveolar Bone Loss - pathology Alveolar bone regeneration Alveolar Process - diagnostic imaging Alveolar Process - pathology Animals Apical root cementum apposition Computed tomography Imaging, Three-Dimensional Ligation Ligature-induced periodontal injury model Male Mice Mice, Inbred C57BL Periodontal disease Tooth Root - diagnostic imaging Tooth Root - pathology X-Ray Microtomography - methods Alveolar bone regeneration 3D Slicer Ligature-induced periodontal injury model Periodontal disease Apical root cementum apposition Computed tomography
ISSN:	8756-3282, 1873-2763, 1873-2763
Online Access:	Get full text
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