The role of adjuvant therapy in Stage I ovarian cancer
Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and se...
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| Veröffentlicht in: | American journal of obstetrics and gynecology Jg. 138; H. 2; S. 139 |
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| Format: | Journal Article |
| Sprache: | Englisch |
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United States
15.09.1980
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| ISSN: | 0002-9378 |
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| Abstract | Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy. |
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| AbstractList | Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy. Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy.Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy. |
| Author | Creasman, W T Blessing, J A Park, R C Hreshchyshyn, M M Levy, D Norris, H J Lagasse, L D |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/6252780$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Adenocarcinoma - drug therapy Adenocarcinoma - radiotherapy Adenocarcinoma, Mucinous - therapy Cystadenocarcinoma - therapy Endometriosis - therapy Female Humans Neoplasm Recurrence, Local - prevention & control Neoplasm Staging Ovarian Neoplasms - drug therapy Ovarian Neoplasms - radiotherapy |
| Title | The role of adjuvant therapy in Stage I ovarian cancer |
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