The role of adjuvant therapy in Stage I ovarian cancer

Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and se...

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Bibliographic Details
Published in:	American journal of obstetrics and gynecology Vol. 138; no. 2; p. 139
Main Authors:	Hreshchyshyn, M M, Park, R C, Blessing, J A, Norris, H J, Levy, D, Lagasse, L D, Creasman, W T
Format:	Journal Article
Language:	English
Published:	United States 15.09.1980
Subjects:	Adenocarcinoma - drug therapy Adenocarcinoma - radiotherapy Adenocarcinoma, Mucinous - therapy Cystadenocarcinoma - therapy Endometriosis - therapy Female Humans Neoplasm Recurrence, Local - prevention & control Neoplasm Staging Ovarian Neoplasms - drug therapy Ovarian Neoplasms - radiotherapy
ISSN:	0002-9378
Online Access:	Get more information
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Summary:	Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3
ISSN:	0002-9378
DOI:	10.1016/0002-9378(80)90024-1