Cigarette Smoke Exposure Attenuates Cytokine Production by Mouse Alveolar Macrophages

Alveolar macrophages (aMs) play a central role in respiratory host defense by sensing microbial antigens and initiating immune-inflammatory responses early in the course of an infection. The purpose of this study was to investigate the effect of cigarette smoke exposure on aMs after stimulation of i...

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Bibliographic Details
Published in:	American journal of respiratory cell and molecular biology Vol. 38; no. 2; pp. 218 - 226
Main Authors:	Gaschler, Gordon J, Zavitz, Caleb C. J, Bauer, Carla M. T, Skrtic, Marko, Lindahl, Maria, Robbins, Clinton S, Chen, Biao, Stampfli, Martin R
Format:	Journal Article
Language:	English
Published:	United States Am Thoracic Soc 01.02.2008 American Thoracic Society
Subjects:	Animals Carboxyhemoglobin - metabolism Cytokines - biosynthesis Cytokines - metabolism Enzyme-Linked Immunosorbent Assay Female Fluorescent Antibody Technique Macrophages, Alveolar - metabolism Macrophages, Peritoneal - metabolism Mice Mice, Inbred C57BL Nicotiana Nitric Oxide - metabolism Pulmonary Disease, Chronic Obstructive - etiology Reverse Transcriptase Polymerase Chain Reaction Smoke - adverse effects Toll-Like Receptors - metabolism
ISSN:	1044-1549, 1535-4989, 1535-4989
Online Access:	Get full text
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