The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril

Amyloids are ordered protein aggregates, found in all kingdoms of life, and are involved in aggregation diseases as well as in physiological activities. In microbes, functional amyloids are often key virulence determinants, yet the structural basis for their activity remains elusive. We determined t...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) Jg. 355; H. 6327; S. 831
Hauptverfasser:	Tayeb-Fligelman, Einav, Tabachnikov, Orly, Moshe, Asher, Goldshmidt-Tran, Orit, Sawaya, Michael R, Coquelle, Nicolas, Colletier, Jacques-Philippe, Landau, Meytal
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 24.02.2017
Schlagworte:	Amyloid - chemistry Amyloid - metabolism Bacterial Toxins - chemistry Bacterial Toxins - metabolism Cells, Cultured Crystallography, X-Ray Humans Protein Conformation Staphylococcus aureus - metabolism Staphylococcus aureus - pathogenicity T-Lymphocytes - microbiology
ISSN:	1095-9203, 1095-9203
Online-Zugang:	Weitere Angaben
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