Pan-cancer Transcriptomic Predictors of Perineural Invasion Improve Occult Histopathologic Detection

Perineural invasion (PNI) is associated with aggressive tumor behavior, recurrence, and metastasis, and can influence the administration of adjuvant treatment. However, standard histopathologic examination has limited sensitivity in detecting PNI and does not provide insights into its mechanistic un...

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Bibliographic Details

Published in:	Clinical cancer research Vol. 27; no. 10; p. 2807
Main Authors:	Guo, Jimmy A, Hoffman, Hannah I, Shroff, Stuti G, Chen, Peter, Hwang, Peter G, Kim, Daniel Y, Kim, Daniel W, Cheng, Stephanie W, Zhao, Daniel, Mahal, Brandon A, Alshalalfa, Mohammed, Niemierko, Andrzej, Wo, Jennifer Y, Loeffler, Jay S, Fernandez-Del Castillo, Carlos, Jacks, Tyler, Aguirre, Andrew J, Hong, Theodore S, Mino-Kenudson, Mari, Hwang, William L
Format:	Journal Article
Language:	English
Published:	United States 15.05.2021
Subjects:	Biomarkers, Tumor Computational Biology - methods Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Machine Learning Neoplasm Invasiveness Neoplasms - diagnosis Neoplasms - genetics Neoplasms - mortality Nerve Tissue - pathology Prognosis Proportional Hazards Models ROC Curve Transcriptome
ISSN:	1557-3265, 1557-3265
Online Access:	Get more information
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